Abstract

Arídio M. Júnior , Flávia A. do Carmo , Lúcio M. Cabral , Maria Inês B. Tavares , Ailton de S. Gomes , Luciano A. M. Grillo , and Camila B. Dornelas*

Polymer (PVP K-30) - organophilic clay nanocomposites were prepared, via solution, in which the influence of time from the mixing of the starting materials was studied. With the help of X-ray diffraction techniques (XRD) and Fourier Transform Infrared Spectroscopy (FTIR), it was possible not only to elucidate the formation of polymeric nanocomposites, but also their process of formation, which occur in short spaces of time. The material resulted in a differential combination of substances with different aspects of functionality in Pharmaceutical Technology, and which resulted in favorable results regarding feasibility as an adjuvant in pharmaceutical formulas, helping the bioavailability of pharmaceuticals with low solubility in water, for both immediate release tablets as well as modified release tablets.