Benign monoclonal gammopathy in a dog exhibiting a low antibody titer to EHRLICHIA CANIS


Stephanie Ng, Sophia Lim, Allison Daub, Surinder S. Saini and Azad K. Kaushik1,*

The occurrence of a remarkable benign γ-monoclonal gammopathy in a 2.5-year-old intact male bichon frise dog, secondary to acute EHRLICHIA CANIS infection, with no travel history outside of Ontario. Exceptionally high levels of serum IgG (104.0 g/ L) as a result of benign monoclonal gammopathy were noted during the disease state that returned to normal subsequent to recovery. Treatment with doxycyline and prednisone resulted in complete recovery and disappearance of the monoclonal gammopathy. In conclusion, such a recovery from monoclonal gammopathy due to infection is indeed promising since very high serum IgG concentrations can be brought back to physiological levels by therapeutic intervention

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