Abstract

1,2Rodrigue Pierre*, 1C Perry Brown, 1Charlotte Baker, 1Matthew Dutton, 2Oghenekome Onokpise, 3Brian Hickey

Despite the many cardiovascular studies conducted in the United States (US), nationally representative estimates of incidence of coronary heart disease (CHD) have been lacking. This study aimed at investigating incidence estimates of CHD in a nationally representative sample of the US population and to compare raceand sex-related incidence estimates. We used data from the First National Health and Nutrition Examination Survey Epidemiologic Follow-Up Study (NHEFS) [n = 6,346]. We determined cumulative incidence and incidence density and used log-rank and chi-square test for estimates comparison. A total of 382 CHD events occurred among 6,346 study participants from 1971 to 1992. The cumulative incidence was 9.93% in the NHEFS cohort; 13.46% among men and 7.00% among women (P< .001); 9.72% among Whites and 11.01% among non-Whites (P = .64). The incidence density, per 1,000 person-years, was 3.68 in the NHEFS cohort; 4.99 among men and 2.66 among women (P< .001); 3.65 among Whites and 3.90 among non-Whites (P = .67). From 1971 to 1992 in the US, the cumulative incidence of CHD was 9.93% and the incidence density was 3.68 per 1,000 person-years. While CHD incidence did not vary across race, males had a higher incidence than females.