The effect of local application of hyaluronan gel as an adjunctive to scaling and root planing in chronic periodontitis patients

Abstract


Basheer Omer, Asim Satti, Bakri Gismalla and Nada Hashim

Background: Chronic Periodontitis is a common disease which might lead to tooth loss if it is not treated. Nonsurgical mechanical therapy is the cornerstone of periodontal treatment. Increasing pocket depth and complicating anatomical factors limit the effectiveness of scaling and root planing (SRP) thereby compromising the results. Hyaluronic Acid (HA) is a recent addition to the local chemotherapeutic agents used in oral diseases. HA has shown good results in patients with chronic gingivitis and it has been used as a scaffold in periodontal tissue regeneration. The aim of this study was to evaluate the adjunctive effect of local application of HA gel following scaling and root planing in chronic periodontitis patients. Method:This is a randomized split mouth clinical trial where a total of 33 patients diagnosed with chronic periodontitis were enrolled. All patients received full mouth SRP and pockets more than 4 mm were selected for HA application. The selected sites were randomly divided into Group A (experimental group) and Group B (control group). For the experimental sites 1 ml of 0.2% hyaluronic acid was applied. Periodontal parameters (PI, GI, PPD, CAL) were recorded at baseline and 6 weeks postoperatively. Results: There was a significant decrease in the mean PDD and mean CAL values from baseline to 6th week in test group (P = 0.001) however no significant difference was observed in mean PPD and CAL among control group (p=0.292, 0.06) respectively. Conclusion: The adjunctive application of HA may have positive effects on probing depth reduction and attachment gain.

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