Clinico-pathological profile of lung cancer in a tertiary medical centre in India: Analysis of 266 cases

Abstract


Bhattacharyya Sujit Kumar*, Mandal Abhijit, Deoghuria Debasis, Agarwala Abinash, Aloke Gopal Ghoshal and Dey Subir Kumar

Lung cancer stands one of the most common malignancies causing very high morbidity and mortality. An increase in the incidence of lung cancer has been observed in India. The aim of this study is to evaluate the clinico-pathological profile of lung cancer attended in a tertiary referral centre in India. A retrospective analysis was done over those patients who were histopathologically proved cases of primary lung carcinoma. The outpatient and inpatient of the department of Pulmonary Medicine in a tertiary medical college attended during the period from January 2008 to December 2009. A total of 266 cases were studied, and the male to female ratio was 6.6:1. The major age group involved was 41-60 years (52.63%) and the rest were below 40 years group (2.63%). The commonest clinical symptom was cough (68.42%).The most common radiological finding in the chest was a mass or space occupying lesion (55.26%). In most cases there was a history of smoking (81.2%). Commonest mode of diagnosis was made by imaging guided fine needle aspiration cytology in 170 patients (63.91%).The most common histological type of lung cancer was squamous cell carcinoma (35.34%). Majority of cases were diagnosed in the later stages of diseases (71.8%). It was found that squamous cell carcinoma was the most frequent histological type .History of smoking was found in majority of patients. Major patients were diagnosed at the later stages of disease (Stage 3B or 4).

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