Abstract

Jayawardena G.R.M.U.G.P , Guruparan , Sumathipala W.L.D.S , Ratnasiri U.D.Pand Senanayake H.M

The aim of this prospective descriptive cross sectional study was to investigate the utility of a single value non fasting glucose tolerance test as described by the Diabetes in Pregnancy Study Group of India (DIPSI) in detecting GDM. Sample of 165 pregnant women between 24-28 weeks of gestation was recruited from a tertiary care maternity hospital in Sri Lanka. All women had the DIPSI and standard OGTT tests performed within a one week and results compared using standard non parametric tests. According to the IADPSG criteria 20% (33/165) had GDM, compared to 22.4% (37/165) detected by DIPSI. Sensitivity of DIPSI criteria was 64% while specificity was 88%. The area under receiver operator curve was 0.8. The mean satisfaction for DIPSI was of 8.9 ± 0.4, compared to 4.7 ± 1.3 for OGTT (p<0.001). Analysis of false positives showed that it was mainly due to elevated fasting values in the IADPSG criteria. Although DIPSI has a low sensitivity compared to the IADPSG criteria, area under the ROC curve is 0.80 indicating its utility for diagnosing GDM. It has additional advantages of allowing a diagnosis of GDM in a single visit and high acceptability among women.