Abstract

D. Kubmarawa *, M. E. Khan , A. M. Punah and Hassan

Pakia clapperotoniana keay has medicinal properties for the effective management of several ailments including tuberculosis. To establish the pharmacological rationale, for its traditional use, the powdered root, stem- bark and leaves were extracted with water and ethanol. All fractions were subjected to phytochemical screening and antimicrobial activity against, Gram-positive and Gram-negative bacteria using the disc-diffusion method. The extracts contained saponnins, tannins, flavanoids, glycosides but no resin. The roots and stembark fractions were more active on Staphylococcus aureus, Streptococcus spp., Escherichia coli, Pseudomonas aeruginosa, Salmonella spp. and Baccilus subtilis, than the leaves fraction. These findings support the claim for its treatment of bacterial and fungal infections.