Schistosoma mansoni infection and hematological profile in an endemic foci in Western Burkina Faso

Abstract


Hermann Sorgho*, Ollo Da, Toussaint Rouamba, Boubacar Savadogo, Halidou Tinto and Jean-Bosco Ouedraogo

Persistence of light infections of Schistosoma mansoni is common among individuals living in endemic settings despite the mass drug treatment with praziquantel. Therefore, it is of interest to understand the impact of S. mansoni on general health indicators such as hematological profile. In the present study, we investigated the impact of S. mansoni infection on complete blood counting an endemic foci in Western Burkina Faso. The results showed among schistosomiasis endemic population, in addition to anemia, participants having poor hematological profile had higher risk of being infected by S. mansoni (OR = 1.71; 95% CI 1.27 – 2.3; P = 0.0003). Conversely, S. mansoni positive subjects had a higher risk of harboring poor hematological profile (OR = 1.49; 95% CI 1.06 – 2.10; P = 0.023) when adjusted by age, gender and water contact. A longer follow-up would allow a better understanding of the long-term impact of schistosomiasis control program on important health indicators such as hematological profile.

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