Abstract

N. E. J. Orhue, E. A. C. Nwanze, A. Okafor

The effect of orally administered Scoparia dulcis on Trypanosoma brucei-induced changes in serum total protein, albumin and globulin were investigated in rabbits over a period of twenty eight days. Results obtained show that infection resulted in hyperproteinaemia, hyperglobulinaemia and hypoalbuminaemia. However these lesions were less severe (p<0.05) in the infected and treated group relative to their untreated counterparts. We speculate that the herb may be involved in modulating the severity of these trypanosome associated lesions by some yet undefined mechanisms