The role of SEF14 fimbriae in pathogenesis and enhancing the immunity of Salmonella enteritidis


Zhu CH, Hassan H. Musa , Wu SL and Zhu GQ*

Food safety is an important component of effective prevention and control strategy for Salmonella enteritidis infection. The control strategies have been implemented in poultry with ultimate aim to reduce S. enteritidis out breaks in human. SEF14 fimbriae are expressed on strains of serogroup D salmonella and contribute their survival in macrophages. SEF14 fimbriae are immunogenic in the S. enteritidis infected chicken. SEF14 antibodies is protective in mice, IgA and IgG response were found in sera of immunized chicken with SEF14 antigen. In this review we concluded that the immunogenecity of SEF14 antigens in the infected birds may serve as component of an effective sub-cellular vaccine for poultry.

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