Antibacterial action of an aqueous grape seedpolyphenolic extract


Veronica Sanda Chedea,*, Cornelia Braicu, Flore ChirilÇ?, Ciprian Ober and Carmen Socaciu

The potential of a polyphenolic grape seed extract for use as a natural antibacterial agent was evaluated. Pure catechin (CS) and a previously LC-MS characterized grape seed phenolic extract (PE) were evaluated as antibacterial agents against ESCHERICHIA COLI and BREVIBACTERIUM LINENS on solid and in liquid culture media. After 48 h incubation on solid medium, PE had a bactericidal effect on the gram positive B. LINENS and a reduction of the microbial growth for E. COLI. The antibacterial agents tested were effective against E. COLI for 13 h, after 7 h incubation, but ineffective against B.LINENS in liquid medium. CS and PE both had an antibacterial effect depending on incubation time.

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