Medication-induced neurotoxicity: Adverse reactions to drug therapy


Mary M. Rezk*

The drug-based treatment methods which have revolutionized modern medicine are vital in effective medical practice. While the use of drug therapy has benefited multitudes since its inception, it is imperative to note the consequences of chronic substance administration. Synthetic medications such as antibiotics, cancer-treating agents, and psychoactive modifiers are all linked to drug-induced neurotoxicity in patients. This results in adverse reactions that significantly increase morbidity, and in some cases, mortality. The potential implications associated with the use of select drugs within each corresponding class will be discussed. Examples of these select medications and their clinical intervention mechanisms are reviewed, and a recently published case report will be introduced for analysis of clinical presentation respective to each category. Analysis of literary review demonstrates correlation and causation between neurotoxicity and chronic medication use. These findings warrant cautionary administration of drugs in clinical practice, and call for increased research in efforts to advance recognition of drug-induced neurotoxicity in patients.

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