Abstract

Ouattara B, Yao KH, Kra O, Konan S, Kouassi L, Kone S, Diallo DA, Kadjo KA, Niamkey EK.

HIV-associated glomerular nephropathy is a cause of chronic kidney failure increasingly described since the advent of HIV infection. The aims of this study was to determinate its prevalence in chronic kidney failure in a Department of Internal Medicine. It was a retrospective transversal study conducted from January 2007 to December 2012 in the Department of Internal Medicine of the University Teaching Hospital of Treichville on medical data of the patients admitted for chronic kidney failure with HIV-associated glomerular nephropathy. Of 335 patients followed up, 74 of them exhibited HIV-associated glomerular nephropathy (17%). The median age was 36±8 years and the sex-ratio was 0.23. A positive retroviral status was discovered in the regression of glomerular nephropathy in 44 patients (59.5%). For 48.3% of cases, chronic kidney failure was the hospitalization cause. Clinical signs at admission were dominated by clinical anemia (80.6%) and edemas of lower limbs (51.6%). The average proteinuria was 7.86 ±5.5 grams per 24 hours. According to the K/DOQI, kidney failure was at stage V in 64.5% of the cases. The mortality was 32.5%. HIV-associated glomerular nephropathy was a frequent cause of chronic kidney failure in our study and of poor prognosis.