AKO A. Aristide Berenger

Department of Microbial Genomics and Metagenomics, Institut Pasteur of Cote d Ivoire, Abidjan, Cote D'Ivoire

Publications

• Research Article   
  High proportion of pfpm-2 multiple-copies carrying isolates, a piperaquine resistance marker, prior dihydroartemisiniepiperaquine adoption in Cote d’Ivoire in 2018
  Author(s): Koui T. Stephane, AKO A. Aristide Berenger*, Kouman KB Angelo, ASSI S-Brice, Ouattara Yacouba, Gbessi A.Eric, N Guessan T. Landry, YAO S. Stephane, Trebissou N.D. Johnson, Beourou Sylvain and Toure A. Offianan
  
  Introduction: In recent years, the therapeutic arsenal used to fight against malaria in Côte d'Ivoire has been enriched with several Artemisinin-Based Combinated Treatment (ATCs), all of which are well-tolerated. The sensitivity of P. falciparum to these molecules was even confirmed by molecular and phenotypic tests in force. However, these tests only evaluate the sensitivity of artemisinin derivatives and not that of the partner molecule. One of these ATCs, Dihydroartemisinin-Piperaquine (DHA-PPQ), was officially introduced in 2018 for the management of uncomplicated malaria and deployed throughout the country. This study aims to test the hypothesis that pfpm2 multiple copies carrying isolates, one of the molecular markers of resistance to PPQ, were circulating well before its official introduction. Methodology: .. View More»
  

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